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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク GWAS in allergy ： ウィキペディア英語版 GWAS in allergy GWAS in allergy is a study of a meta-analysis of GWAS in which allergy is associated with different susceptibility loci . The three allergic phenotypes studied were to cat, dust mites and pollen, for which found patients presenting allergic symptoms.〔De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I., Ottoboni, L., Aggarwal, N. T., ... & Oksenberg, J. R. (2009). Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nature genetics, 41(7), 776-782.〕 == History == Allergy is a very common disease and leads to numerous health problems, with allergies and allergic asthma are the two most common diseases in the industrialized world, where half of the population of United States tested positive in a test of awareness for at least one common allergen. It has been shown that this type of disease has risen in prevalence over the past ten years. Furthermore, is estimated that allergy has a hereditary component, suggesting that knowledge of the genetic component is a key to understand the disease. It has been shown that the genes involved in allergy and asthma, are implicated in both immune and inflammatory processes . These genes belong to the family of Toll receptors ( LTRs ) type, a family of proteins that form part of the innate immune system . These receptors are transmembrane and recognize molecular patterns expressed by a wide spectrum of infectious agents, thereby stimulating inflammatory responses, as well as being a link between innate and adaptive immunity . Apart from these receptors, associated with allergy genes encoding cytokines, chemokines and other transcription factors occur.〔De Jager, P. L., Jia, X., Wang, J., de Bakker, P. I., Ottoboni, L., Aggarwal, N. T., ... & Oksenberg, J. R. (2009). Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nature genetics, 41(7), 776-782.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「GWAS in allergy」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.